Used in clinical diagnostics to detect the presence of Rhesus D (RhD) antigen on red blood cells, this antibody plays a critical role in blood typing. It ensures accurate matching for blood transfusions and prevents hemolytic reactions in recipients. Widely applied in prenatal testing to identify RhD status in pregnant women, helping to manage risk of hemolytic disease of the newborn (HDN). Also utilized in laboratory research for flow cytometry, immunohistochemistry, and cell separation techniques involving RhD-positive cells. Its high specificity supports reliable identification and characterization of erythroid lineage cells in various hematological studies.