17-DMAG (Alvespimycin) HCl
≥98%
Reagent
Code: #76967
CAS Number
467214-21-7
blur_circular Chemical Specifications
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Molecular Information
Weight
653.21 g/mol
Formula
C₃₂H₄₈N₄O₈HCl
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in cancer research, it acts as an inhibitor of heat shock protein 90 (HSP90), a protein that supports tumor growth. It is studied for its potential to disrupt cancer cell survival by degrading client proteins essential for tumor progression. Additionally, it is explored in combination therapies to enhance the effectiveness of other anticancer drugs. Its role in neurodegenerative diseases is also under investigation, as HSP90 inhibition may help in managing conditions like Alzheimer’s and Parkinson’s by reducing protein misfolding and aggregation.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Very Dark Purple Solid |
| Purity | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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