Gamitrinib TPP

98%

Reagent Code: #60303
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CAS Number 1131626-46-4

science Other reagents with same CAS 1131626-46-4

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Weight 891.0599999999999 g/mol
Formula C₅₂H₆₅N₃O₈P
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Gamitrinib TPP is primarily utilized in the field of cancer research and therapy due to its targeted action on heat shock proteins (HSPs) within mitochondria. It is designed to inhibit the function of HSP90, a chaperone protein that plays a critical role in the stability and function of various oncogenic proteins. By disrupting HSP90 activity in mitochondria, Gamitrinib TPP induces mitochondrial dysfunction and triggers apoptosis specifically in cancer cells, sparing normal cells. This selective mechanism makes it a promising candidate for treating tumors that are resistant to conventional therapies. Its application is particularly significant in preclinical studies aimed at understanding and combating drug-resistant cancers, such as those in breast, prostate, and pancreatic malignancies.

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿39,900.00
inventory 5mg
10-20 days ฿114,000.00

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Gamitrinib TPP
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Gamitrinib TPP is primarily utilized in the field of cancer research and therapy due to its targeted action on heat shock proteins (HSPs) within mitochondria. It is designed to inhibit the function of HSP90, a chaperone protein that plays a critical role in the stability and function of various oncogenic proteins. By disrupting HSP90 activity in mitochondria, Gamitrinib TPP induces mitochondrial dysfunction and triggers apoptosis specifically in cancer cells, sparing normal cells. This selective mechanis

Gamitrinib TPP is primarily utilized in the field of cancer research and therapy due to its targeted action on heat shock proteins (HSPs) within mitochondria. It is designed to inhibit the function of HSP90, a chaperone protein that plays a critical role in the stability and function of various oncogenic proteins. By disrupting HSP90 activity in mitochondria, Gamitrinib TPP induces mitochondrial dysfunction and triggers apoptosis specifically in cancer cells, sparing normal cells. This selective mechanism makes it a promising candidate for treating tumors that are resistant to conventional therapies. Its application is particularly significant in preclinical studies aimed at understanding and combating drug-resistant cancers, such as those in breast, prostate, and pancreatic malignancies.

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