MKT-077 is primarily studied for its potential applications in cancer research and therapy. It functions as a selective inhibitor of heat shock protein 70 (Hsp70), a protein that plays a critical role in cell survival and stress response. By inhibiting Hsp70, MKT-077 disrupts the protective mechanisms of cancer cells, making them more susceptible to apoptosis (programmed cell death). This makes it a promising candidate for developing targeted cancer treatments, particularly for tumors that rely heavily on Hsp70 for growth and survival. Additionally, MKT-077 has been explored in research to understand its effects on neurodegenerative diseases, as Hsp70 is also implicated in protein misfolding and aggregation, which are hallmarks of conditions like Alzheimer's and Parkinson's diseases. Its ability to modulate protein homeostasis makes it a valuable tool in both therapeutic and experimental contexts.