RGFP966 is primarily utilized in research settings to study its role as a selective inhibitor of histone deacetylase 3 (HDAC3). Its application is significant in the field of neuroscience, where it is used to investigate the mechanisms underlying memory formation, neuroplasticity, and cognitive functions. Researchers employ RGFP966 to explore its potential in mitigating neurodegenerative diseases, such as Alzheimer's, by modulating gene expression linked to neuronal health. Additionally, it is studied in cancer research to understand its effects on cell differentiation and apoptosis, particularly in relation to HDAC3's role in tumor progression. Its use extends to behavioral studies, where it helps elucidate the impact of epigenetic modifications on stress responses and addiction. Overall, RGFP966 serves as a valuable tool in advancing our understanding of epigenetic regulation in various biological processes.