Suberoylanilide Hydroxamic Acid
10mM in DMSO
Reagent
Code: #234095
CAS Number
149647-78-9
blur_circular Chemical Specifications
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Molecular Information
Weight
264.33 g/mol
Formula
C₁₄H₂₀N₂O₃
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Registry Numbers
MDL Number
MFCD00945317
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in research as a potent histone deacetylase (HDAC) inhibitor, it plays a key role in regulating gene expression by increasing histone acetylation. This activity makes it valuable in studying cancer cell apoptosis, cell cycle arrest, and differentiation in various tumor models. It has shown activity in preclinical studies against hematological malignancies and solid tumors, supporting its use as a tool compound in oncology research. Additionally, it is used to investigate epigenetic mechanisms in neurological diseases, inflammation, and cardiac hypertrophy. Due to its ability to modulate protein acetylation, it aids in understanding chromatin remodeling and transcriptional regulation. Not intended for diagnostic or therapeutic use in humans.
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