Entinostat (MS-275)
≥98%
Reagent
Code: #182131
CAS Number
209783-80-2
blur_circular Chemical Specifications
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Molecular Information
Weight
376.41 g/mol
Formula
C₂₁H₂₀N₄O₃
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Registry Numbers
MDL Number
MFCD03453552
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Storage & Handling
Storage
-20°C
description Product Description
Used in cancer research, particularly for its potential in treating solid tumors and hematological malignancies. It functions as a histone deacetylase (HDAC) inhibitor, which helps reactivate silenced tumor suppressor genes. Often studied in combination with other therapies such as hormone therapy, immunotherapy, or chemotherapy to enhance anti-tumor effects. Shows promise in breast cancer, lung cancer, and melanoma by improving immune recognition of cancer cells and reducing tumor growth. Also investigated for its ability to reverse drug resistance in certain cancers.
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