Tenovin-2 is primarily utilized in research settings for its role as an inhibitor of sirtuin activity, particularly SIRT1 and SIRT2. This property makes it valuable in studies focused on understanding the mechanisms of aging, cancer, and metabolic disorders. By inhibiting sirtuins, Tenovin-2 helps researchers explore the impact of these proteins on cellular processes such as DNA repair, apoptosis, and stress resistance. Additionally, it has been investigated for its potential to induce p53 activation, a tumor suppressor protein, which could be beneficial in cancer therapy research. Its application extends to studying neurodegenerative diseases, where sirtuin modulation is thought to play a role in disease progression. Overall, Tenovin-2 serves as a critical tool in biomedical research for dissecting the complex roles of sirtuins in health and disease.