HDAC8-IN-1 is primarily used in research settings to study the role of histone deacetylase 8 (HDAC8) in various biological processes. It serves as a selective inhibitor of HDAC8, making it a valuable tool for investigating the enzyme's function in cellular mechanisms such as gene expression, cell cycle regulation, and epigenetic modifications. Researchers utilize this compound to explore its potential therapeutic applications in diseases where HDAC8 is implicated, including certain cancers, neurodegenerative disorders, and genetic conditions. Additionally, HDAC8-IN-1 aids in the development of targeted therapies by providing insights into the inhibition of HDAC8 and its effects on cellular pathways. Its application extends to drug discovery, where it helps in identifying and optimizing new compounds for HDAC8-related treatments.