Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its halogen substituents (chloro, difluoro, and iodo) allow for selective cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex pyridine-based structures. Commonly employed in Suzuki and Buchwald–Hartwig reactions to introduce aryl or amino groups. Also utilized in agrochemical research for designing novel active ingredients due to its electron-deficient aromatic core and reactivity profile.