4,5-Difluoro-2-iodophenol
95%
Reagent
Code: #176260
CAS Number
186590-30-7
blur_circular Chemical Specifications
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Molecular Information
Weight
255.9900 g/mol
Formula
C₆H₃F₂IO
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Registry Numbers
MDL Number
MFCD23135549
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Physical Properties
Boiling Point
201.1±35.0 °C at 760 mmHg
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Storage & Handling
Density
2.2±0.1 g/cm3
Storage
2-8°C, away from light, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated drug candidates where the iodine allows for further functionalization via cross-coupling reactions. Its difluoro substitution pattern enhances metabolic stability and membrane permeability in bioactive molecules. Commonly employed in the preparation of kinase inhibitors and other targeted therapies. Also utilized in agrochemical research for designing novel active ingredients with improved environmental persistence and efficacy. The phenolic group enables easy derivatization for building complex molecular architectures.
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