5-Cyano-2-fluorobenzoic acid
97%
Reagent
Code: #160225
CAS Number
146328-87-2
blur_circular Chemical Specifications
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Molecular Information
Weight
165.12 g/mol
Formula
C₈H₄FNO₂
thermostat
Physical Properties
Boiling Point
322.1°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors. Its structure, featuring cyano, fluoro, and carboxylic acid groups, allows for easy functionalization, especially nucleophilic substitution at the ortho-fluoro position, making it valuable in building complex molecules in medicinal chemistry. Also employed in the preparation of agrochemicals and fluorescent dyes due to its electron-withdrawing nitrile, fluoro, and carboxylic acid groups, which enhance reactivity and binding properties.
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