Used primarily as a reagent in organic synthesis, 2-Fluoro-5-nitrobenzoyl chloride is instrumental in the preparation of various pharmaceutical intermediates. Its reactive acyl chloride group facilitates the formation of amides and esters, making it valuable in the development of active pharmaceutical ingredients (APIs). Additionally, it is employed in the synthesis of agrochemicals and dyes, where its nitro and fluoro substituents enhance the reactivity and specificity of the resulting compounds. The chemical is also utilized in research for modifying peptides and proteins, aiding in the study of biochemical pathways and drug discovery.