1-Bromo-5-fluoronaphthalene is primarily utilized in organic synthesis as a versatile building block for the development of complex chemical structures. Its unique combination of bromine and fluorine substituents on the naphthalene ring makes it a valuable intermediate in the preparation of pharmaceuticals, agrochemicals, and advanced materials. The bromine atom serves as a reactive site for cross-coupling reactions, such as Suzuki or Heck reactions, enabling the introduction of various functional groups. Meanwhile, the fluorine atom enhances the stability and bioavailability of the resulting compounds, making it particularly useful in drug discovery. Additionally, this compound is employed in the synthesis of fluorescent dyes and organic electronic materials due to its aromatic structure and electron-withdrawing properties. Its applications also extend to research in material science, where it is used to develop novel polymers and liquid crystals.