5-Fluoro-2-(trifluoromethyl)benzenesulfonyl chloride
90%(NMR)
Reagent
Code: #189839
CAS Number
915763-87-0
blur_circular Chemical Specifications
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Molecular Information
Weight
262.61 g/mol
Formula
C₇H₃ClF₄O₂S
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Registry Numbers
MDL Number
MFCD13185646
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Storage & Handling
Storage
Room temperature, inert gas
description Product Description
Used primarily as a key intermediate in the synthesis of sulfa drugs and agrochemicals. Its electrophilic sulfonyl chloride group readily reacts with amines to form sulfonamides, which are important structural motifs in pharmaceuticals. Particularly valuable in the preparation of fluorinated bioactive compounds, where the fluorine atoms enhance metabolic stability and membrane permeability. Also employed in the development of herbicides and fungicides due to the combined effect of fluorine and sulfonyl functionalities, improving lipophilicity and target binding. Commonly used in medicinal chemistry for building blocks in drug discovery programs targeting enzyme inhibitors.
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