3-Fluoro-4-methoxybenzyl Chloride
98%(GC)(T)
Reagent
Code: #187910
CAS Number
351-52-0
blur_circular Chemical Specifications
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Molecular Information
Weight
174.60 g/mol
Formula
C₈H₈ClFO
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Registry Numbers
MDL Number
MFCD04973773
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Physical Properties
Melting Point
25°C(凝固点)
Boiling Point
62°C|0.2mmHg(lit.)
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Storage & Handling
Storage
Room temperature, dryness, inert gas storage
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals, especially in the development of active pharmaceutical ingredients (APIs) for central nervous system agents and receptor antagonists. Its structure allows for selective derivatization, making it valuable in constructing complex organic molecules. Commonly employed in the preparation of fluorinated analogs of bioactive compounds to enhance metabolic stability and binding affinity. Also utilized in agrochemical research for designing novel pesticides and herbicides due to the electron-withdrawing effect of the fluorine atom combined with the methoxy group’s influence on lipophilicity. Suitable for use in nucleophilic substitution reactions, enabling the introduction of the 3-fluoro-4-methoxybenzyl moiety into larger molecular frameworks.
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