4-(Difluoromethyl)benzene-1-sulfonyl chloride
95%
Reagent
Code: #178404
CAS Number
1263179-09-4
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the development of fungicides and herbicides. Its sulfonyl chloride group readily reacts with nucleophiles, enabling the formation of sulfonamides and sulfonate esters, which are important structural motifs in bioactive molecules. It is also employed in medicinal chemistry for the introduction of the difluoromethylbenzene sulfonyl moiety to modulate the metabolic stability and lipophilicity of drug candidates.
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