Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated aromatic compounds. Its multiple halogen substituents allow selective cross-coupling reactions, making it valuable in building complex organic molecules for drug discovery. Commonly employed in palladium-catalyzed reactions such as Suzuki and Heck couplings to introduce the difluoroiodobenzene moiety into target structures. Also utilized in materials science for designing liquid crystals and organic semiconductors due to its electronic properties and structural stability.