1-Bromo-2,4-difluoro-5-methoxybenzene
98%
Reagent
Code: #153727
CAS Number
943831-06-9
blur_circular Chemical Specifications
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Molecular Information
Weight
223.01 g/mol
Formula
C₇H₅BrF₂O
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated drug candidates where the bromine atom allows for further functionalization via cross-coupling reactions. Its difluoro-methoxy aromatic structure makes it valuable in building blocks for agrochemicals and bioactive molecules, especially in medicinal chemistry for optimizing metabolic stability and binding affinity. Commonly employed in Suzuki, Heck, and Negishi couplings to introduce the difluorinated anisole moiety into larger, more complex structures. Also utilized in the preparation of liquid crystals and functional materials due to its polarity and electronic properties.
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