4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
98%
Reagent
Code: #146180
CAS Number
335013-18-8
blur_circular Chemical Specifications
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Molecular Information
Weight
317.93 g/mol
Formula
C₈H₅Br₂F₃
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Registry Numbers
MDL Number
MFCD13185414
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as a versatile intermediate in organic synthesis, especially in pharmaceutical and agrochemical industries. Its dual bromine functionality allows for selective cross-coupling reactions, making it valuable in constructing complex aromatic compounds. The presence of a trifluoromethyl group enhances lipophilicity and metabolic stability, which is advantageous in drug design. Commonly employed in Suzuki, Stille, and Negishi couplings to introduce substituted aryl or heteroaryl moieties. Also utilized in the preparation of fluorinated building blocks for materials science and in the development of bioactive molecules with improved pharmacokinetic profiles.
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