1-bromo-2-(methoxymethyl)benzene
98%
Reagent
Code: #144121
CAS Number
52711-30-5
blur_circular Chemical Specifications
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Molecular Information
Weight
201.06 g/mol
Formula
C₈H₉BrO
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Registry Numbers
MDL Number
MFCD03790887
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Physical Properties
Boiling Point
213.0±15.0°C at 760 mmHg
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Storage & Handling
Storage
Room temperature, light-proof
description Product Description
Used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. Its bromine functionality allows for palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, enabling the construction of complex aromatic systems. The methoxymethyl group serves as a protected hydroxymethyl functionality (equivalent to a methyl ether of a benzyl alcohol), which can be deprotected to the free benzyl alcohol using Lewis acids like BBr3. Commonly employed in the development of bioactive molecules where ortho-substituted benzene derivatives are required.
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