2-Bromoindene is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and fine chemicals. It serves as a building block for the synthesis of more complex molecules, often contributing to the development of compounds with potential biological activity. In medicinal chemistry, it is utilized to create indene derivatives that may exhibit therapeutic properties, such as anti-inflammatory or anticancer effects. Additionally, it finds application in material science, where it is employed in the preparation of organic semiconductors and other advanced materials. Its reactivity makes it valuable in cross-coupling reactions, enabling the construction of diverse organic frameworks.