1-Bromo-2,4,6-trifluorobenzene
98%
Reagent
Code: #114735
Alias
2-Bromo-1,3,5-trifluorobenzene 2,4,6-trifluorobromobenzene
CAS Number
2367-76-2
blur_circular Chemical Specifications
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Molecular Information
Weight
210.98 g/mol
Formula
BrC₆H₂F₃
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Registry Numbers
EC Number
219-125-9
MDL Number
MFCD00000334
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Physical Properties
Melting Point
3.5 °C(lit.)
Boiling Point
140.5 °C(lit.)
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Storage & Handling
Density
1.79 g/mL at 25 °C(lit.)
Storage
room temperature, flammable area
description Product Description
1-Bromo-2,4,6-trifluorobenzene is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its unique structure, featuring both bromine and fluorine substituents, makes it a valuable building block for creating complex molecules. In the pharmaceutical industry, it is often employed in the development of active pharmaceutical ingredients (APIs) due to its ability to introduce fluorine atoms, which can enhance the biological activity and metabolic stability of drugs. Additionally, it finds use in the synthesis of specialty chemicals and materials, where its halogenated aromatic ring can be further functionalized to create compounds with specific properties. Its role in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, is also notable, enabling the construction of diverse aromatic systems.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (GC) | 98-100% |
| Refractive Index (N20/D) | 1.483-1.485 |
| Specific Gravity (20/20) | 1.796-1.803 |
| Appearance | Colorless to Yellow Liquid |
| Infrared Spectrum | Conforms to Structure |
| Note | This Product Is Low Melting Point Solid, May Change State In Different Environments (Solid, Liquid Or Semi-Solid) |
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