Used as an intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki and Heck reactions, to construct complex aromatic and conjugated systems. Its reactivity stems from the iodine moiety, which readily participates in metal-catalyzed transformations, while the fluorine atom acts as a directing group or remains inert to serve as a functional handle in pharmaceuticals, agrochemicals, and materials science. Commonly employed in the development of liquid crystals, organic semiconductors, and fluorescent dyes due to the naphthalene backbone’s extended π-system. Also utilized in radiolabeling and medical imaging research when isotopically modified.