2-Fluoro-3-(trifluoromethyl)Benzyl Alcohol
≥97%
Reagent
Code: #187865
CAS Number
207981-45-1
science Other reagents with same CAS 207981-45-1
blur_circular Chemical Specifications
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Molecular Information
Weight
194.13 g/mol
Formula
C₈H₆F₄O
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Registry Numbers
MDL Number
MFCD00061166
thermostat
Physical Properties
Melting Point
24-26°C
Boiling Point
211°C
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Storage & Handling
Density
1.38g/mL
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine atoms enhance metabolic stability and bioavailability. Its structure is valuable in agrochemicals for creating herbicides and insecticides with improved efficacy and environmental persistence. The alcohol functional group allows for easy derivatization, making it useful in building blocks for complex organic molecules. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the combined electron-withdrawing effects of fluorine and trifluoromethyl groups, which influence binding affinity and lipophilicity.
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