(2-Bromo-4,5-difluorophenyl)methanol
98%
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Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective kinase inhibitors and antitumor agents. Its bromo and hydroxyl functional groups allow for further chemical modifications, enabling coupling reactions and introduction of fluorinated aromatic systems in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the enhanced metabolic stability and bioavailability imparted by the difluoro substitution pattern. Also utilized in the preparation of radiolabeled compounds for positron emission tomography (PET) imaging probes, where the bromine atom can be substituted with a radioactive isotope.
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