N-Boc-3-bromo-4-fluoroaniline

≥97%

Reagent Code: #173142
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CAS Number 836619-77-3

science Other reagents with same CAS 836619-77-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 290.13 g/mol
Formula C₁₁H₁₃BrFNO₂
badge Registry Numbers
MDL Number MFCD11975628
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated aromatic compounds with biological activity. The Boc-protected amine group allows for selective reactions at other sites on the molecule, while the bromo substituent enables further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in medicinal chemistry for constructing complex molecules in drug discovery programs, especially in the development of kinase inhibitors and other bioactive agents. Its fluorinated aromatic core contributes to improved metabolic stability and binding affinity in final active compounds.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿1,820.00
inventory 5g
10-20 days ฿6,600.00
inventory 10g
10-20 days ฿12,750.00
inventory 25g
10-20 days ฿28,570.00

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N-Boc-3-bromo-4-fluoroaniline
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated aromatic compounds with biological activity. The Boc-protected amine group allows for selective reactions at other sites on the molecule, while the bromo substituent enables further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in medicinal chemistry for constructing complex molecules in drug discovery programs, especially in the development of kinase inhibitors and other bioactive agents. Its fluorinated aromatic core contributes to improved metabolic stability and binding affinity in final active compounds.
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