N-Boc-3-bromo-4-fluoroaniline
≥97%
Reagent
Code: #173142
CAS Number
836619-77-3
science Other reagents with same CAS 836619-77-3
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Molecular Information
Weight
290.13 g/mol
Formula
C₁₁H₁₃BrFNO₂
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Registry Numbers
MDL Number
MFCD11975628
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated aromatic compounds with biological activity. The Boc-protected amine group allows for selective reactions at other sites on the molecule, while the bromo substituent enables further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in medicinal chemistry for constructing complex molecules in drug discovery programs, especially in the development of kinase inhibitors and other bioactive agents. Its fluorinated aromatic core contributes to improved metabolic stability and binding affinity in final active compounds.
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