Sodium 2,2-difluoropropionate is primarily utilized in the field of organic synthesis as a building block for the preparation of more complex fluorinated compounds. Its difluorinated structure makes it valuable in the development of pharmaceuticals, where fluorine atoms are often introduced to enhance the metabolic stability and bioavailability of drugs. Additionally, it is employed in agrochemical research to create novel pesticides and herbicides with improved efficacy and selectivity. The compound also finds use in material science, particularly in the synthesis of fluoropolymers, which exhibit unique properties such as chemical resistance, thermal stability, and low surface energy. Its role in these applications highlights its significance in advancing innovation across various industries.