Ethyl 2-chloro-4,4,4-trifluoroacetoacetate
94%
Reagent
Code: #181870
CAS Number
363-58-6
blur_circular Chemical Specifications
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Molecular Information
Weight
218.56 g/mol
Formula
C₆H₆ClF₃O₃
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Registry Numbers
MDL Number
MFCD00041540
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its structure allows for easy introduction of trifluoromethyl groups, which can enhance metabolic stability and bioavailability in active compounds. Commonly employed in the production of herbicides and insecticides due to the electron-withdrawing effects of the trifluoromethyl group improving pesticidal activity. Also utilized in the preparation of fluorinated beta-keto esters for use in heterocyclic synthesis, particularly in the development of fluorinated analogs of biologically active molecules. Its reactivity makes it suitable for condensation and cyclization reactions in medicinal chemistry.
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