AR-A014418 is primarily used in biochemical research as a selective inhibitor of glycogen synthase kinase-3 beta (GSK-3β). Its application is significant in studying cellular signaling pathways, particularly those involved in diseases like Alzheimer's, diabetes, and cancer. Researchers utilize AR-A014418 to investigate the role of GSK-3β in neuronal survival, insulin regulation, and tumor growth. This compound helps in understanding the molecular mechanisms underlying these conditions, aiding in the development of potential therapeutic strategies. It is also employed in in vitro and in vivo studies to explore its effects on apoptosis, inflammation, and cell proliferation, providing insights into its potential as a drug candidate.