3,4,5-Trifluorophenylmagnesium bromide
0.3 M solution in THF, MkSeal
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This chemical is primarily used as a reagent in organic synthesis, particularly in the formation of carbon-carbon bonds. It is commonly employed in Grignard reactions, where it acts as a nucleophile to react with various electrophiles such as carbonyl compounds (aldehydes, ketones, or esters) to produce alcohols, carboxylic acids, or other complex organic molecules. Its trifluorophenyl group is useful in introducing fluorine atoms into target molecules, which can enhance properties like stability, lipophilicity, and bioavailability in pharmaceuticals and agrochemicals. Additionally, it is utilized in the development of advanced materials, including liquid crystals and polymers, where the fluorine substituents can impart unique electronic and physical characteristics.
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