Used as a non-nucleophilic strong base in organic synthesis, particularly for selective deprotonation and metalation reactions to generate organomagnesium species. It is effective in the formation of carbon-carbon bonds via subsequent reactions with electrophiles, making it valuable in the synthesis of complex organic molecules such as pharmaceuticals and natural products. Commonly employed in the preparation of functionalized organometallic compounds. The lithium chloride complex improves solubility in THF and enables reactions under mild conditions. Its stability and reactivity make it suitable for use in anhydrous and air-sensitive reactions.