Primarily used in organic synthesis as a Grignard reagent, 4-Biphenylmagnesium bromide facilitates the formation of carbon-carbon bonds. It is commonly employed in the preparation of complex biphenyl derivatives, which are essential in the development of pharmaceuticals, agrochemicals, and organic materials. The reagent is particularly useful in coupling reactions, enabling the introduction of biphenyl groups into various organic molecules. Additionally, it plays a role in the synthesis of liquid crystals, polymers, and other advanced materials where biphenyl structures are required for specific properties. Its reactivity with electrophiles makes it a valuable tool in constructing diverse organic frameworks.