Used as a highly active catalyst in cross-coupling reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Its bulky phosphine ligand enhances stability and promotes reactivity under mild conditions. Commonly applied in gold-catalyzed transformations such as alkyne functionalization, cyclization reactions, and C–H activation. The presence of the non-coordinating hexafluoroantimonate anion improves solubility and catalytic efficiency in nonpolar solvents. Preferred in research settings for enabling selective and efficient synthetic pathways in complex organic molecules.