Widely used as a highly active homogeneous catalyst in cross-coupling reactions, particularly in carbon–carbon and carbon–heteroatom bond formations. Its primary application lies in gold-catalyzed transformations where high selectivity and efficiency are required, such as in the synthesis of complex organic molecules, pharmaceuticals, and fine chemicals. The electron-rich phosphine ligand enhances the stability and reactivity of the gold center, allowing the catalyst to promote reactions under mild conditions with excellent functional group tolerance. It is especially effective in coupling reactions involving aryl and heteroaryl substrates, making it valuable in medicinal chemistry and materials science research.