AZ PFKFB3 26 is a potent inhibitor of the PFKFB3 enzyme, which plays a crucial role in regulating glycolysis, a key metabolic pathway in cells. Its primary application lies in cancer research, where it is used to study the effects of inhibiting glycolysis in tumor cells. By blocking PFKFB3, it can potentially reduce the energy supply to cancer cells, thereby inhibiting their growth and proliferation. This makes it a valuable tool for exploring new therapeutic strategies targeting cancer metabolism. Additionally, it is used in research focused on understanding the role of glycolysis in other diseases, such as inflammatory conditions and cardiovascular disorders, where metabolic dysregulation is a contributing factor. Its ability to modulate cellular energy pathways also makes it relevant for studying metabolic adaptations in various biological contexts.