S(−)-Baclofen hydrochloride is primarily used as a muscle relaxant and antispastic agent. It is effective in treating conditions such as multiple sclerosis, spinal cord injuries, and other neurological disorders that cause muscle spasticity. By acting on GABA receptors in the central nervous system, it helps reduce muscle stiffness, spasms, and pain, improving mobility and comfort for patients. Additionally, it is sometimes used off-label to manage conditions like chronic hiccups, alcohol withdrawal, and certain types of neuropathic pain. The compound is typically administered orally or via intrathecal infusion for severe cases, allowing for targeted and effective relief.