Loreclezole is primarily used in research settings to study the mechanisms of GABA_A receptors, which play a crucial role in the central nervous system. It acts as a positive allosteric modulator, enhancing the effects of GABA, the main inhibitory neurotransmitter. This property makes it a valuable tool for understanding epilepsy and other neurological disorders characterized by abnormal neuronal excitability. Additionally, loreclezole has been investigated for its potential anticonvulsant effects, providing insights into the development of new therapeutic agents for seizure management. Its selectivity for certain GABA_A receptor subtypes also aids in exploring the pharmacological diversity of these receptors.