Gabazine is primarily used in neuroscience research as a potent and selective antagonist of GABA_A receptors. It is particularly valuable in studying the role of GABA, the major inhibitory neurotransmitter in the brain. By blocking GABA_A receptors, gabazine helps researchers understand how these receptors influence neuronal excitability, synaptic transmission, and overall brain function. It is widely used in electrophysiological experiments to investigate the mechanisms of GABAergic inhibition and its impact on neural circuits. Additionally, gabazine is employed in studies related to epilepsy, anxiety, and other neurological disorders where GABA signaling is implicated. Its ability to selectively inhibit GABA_A receptors makes it a crucial tool for exploring the therapeutic potential of modulating GABAergic activity.