AMD3465 hexahydrobromide is primarily utilized in research and development within the biomedical field, particularly in the study of chemokine receptors. It acts as a potent and selective antagonist of the CXCR4 receptor, which plays a critical role in various physiological and pathological processes. This compound is extensively used in laboratory studies to investigate the mechanisms of cancer metastasis, as CXCR4 is often implicated in the migration of cancer cells to distant organs. Additionally, it is employed in HIV research, given the involvement of CXCR4 in viral entry into host cells. AMD3465 hexahydrobromide also finds application in stem cell research, where it helps in understanding the role of CXCR4 in stem cell mobilization and homing. Its ability to block CXCR4 signaling makes it a valuable tool for exploring potential therapeutic strategies in oncology, immunology, and regenerative medicine.