1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl]thiourea
≥98%,99%e.e.
Reagent
Code: #70588
CAS Number
1314743-49-1
blur_circular Chemical Specifications
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Molecular Information
Weight
439.5 g/mol
Formula
C₁₉H₂₃F₆N₃S
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Storage & Handling
Storage
room temperature, dry
description Product Description
This compound is primarily utilized in the field of medicinal chemistry, particularly as a selective antagonist for the neurokinin 1 (NK1) receptor. Its application is significant in the development of treatments for conditions such as chemotherapy-induced nausea and vomiting (CINV), as well as in the management of depression and anxiety disorders. The compound's unique structure allows it to effectively bind to the NK1 receptor, inhibiting the action of substance P, a neuropeptide involved in pain and stress responses. Additionally, its stability and bioavailability make it a promising candidate for further pharmaceutical research and drug development.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | white to yellow to brown powder |
| Purity (%) | 98-100 |
| Enantiomeric Excess (%) | 98.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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