1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl]thiourea

≥98%,99%e.e.

Reagent Code: #70588
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CAS Number 1314743-49-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 439.5 g/mol
Formula C₁₉H₂₃F₆N₃S
inventory_2 Storage & Handling
Storage room temperature, dry

description Product Description

This compound is primarily utilized in the field of medicinal chemistry, particularly as a selective antagonist for the neurokinin 1 (NK1) receptor. Its application is significant in the development of treatments for conditions such as chemotherapy-induced nausea and vomiting (CINV), as well as in the management of depression and anxiety disorders. The compound's unique structure allows it to effectively bind to the NK1 receptor, inhibiting the action of substance P, a neuropeptide involved in pain and stress responses. Additionally, its stability and bioavailability make it a promising candidate for further pharmaceutical research and drug development.

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Test Parameter Specification
Appearance white to yellow to brown powder
Purity (%) 98-100
Enantiomeric Excess (%) 98.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿8,379.00

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