ZM241385 is primarily used in research settings as a selective antagonist for the adenosine A2A receptor. It is widely applied in studies focused on understanding the role of adenosine receptors in various physiological and pathological processes. In neuroscience, it helps investigate the receptor's involvement in modulating neurotransmitter release, neuroprotection, and motor control, particularly in conditions like Parkinson's disease. Additionally, it is utilized in cardiovascular research to explore the receptor's impact on vasodilation and heart rate regulation. Its selective antagonism also makes it a valuable tool in cancer research, where adenosine A2A receptor signaling is studied for its role in tumor growth and immune evasion. Overall, ZM241385 serves as a critical compound for elucidating adenosine receptor functions and developing targeted therapies.