JMV 2959 is primarily used in research settings to study the role of the ghrelin receptor (GHS-R1a) in various physiological processes. It acts as a potent antagonist of this receptor, making it a valuable tool for investigating appetite regulation, metabolism, and energy balance. Researchers utilize JMV 2959 to explore its potential effects on reducing food intake and body weight, which could have implications for treating obesity and related metabolic disorders. Additionally, it is employed in studies examining the ghrelin system's involvement in stress responses, addiction, and reward pathways, providing insights into its broader neurological and behavioral impacts.