PMX 205 is primarily utilized in research settings to study inflammatory and immune responses. It acts as a selective antagonist for the C5a receptor, which plays a critical role in the complement system. By inhibiting this receptor, PMX 205 helps researchers understand the mechanisms of inflammation and its impact on various diseases, such as sepsis, rheumatoid arthritis, and neurodegenerative disorders. Its application is particularly valuable in preclinical studies aimed at developing therapeutic strategies to modulate immune responses and reduce inflammation-related tissue damage.