CAL-130 Hydrochloride is a potent and selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), primarily used in biochemical and pharmacological research. PI3Kδ is a key enzyme in cellular signaling pathways involved in immune responses, inflammation, B-cell development, and cancer progression. Researchers utilize CAL-130 Hydrochloride to investigate PI3Kδ-mediated signaling, particularly in the contexts of autoimmune diseases, inflammatory disorders, and oncology, including the regulation of cell proliferation, survival, and migration in cancer cells. Its application supports the elucidation of disease mechanisms and the development of targeted therapeutic strategies for PI3Kδ-related conditions.