5'-N-Ethylcarboxamidoadenosine (NECA) is widely used in research as a potent adenosine receptor agonist. It activates all four subtypes of adenosine receptors (A1, A2A, A2B, and A3), making it a valuable tool for studying adenosine signaling pathways. In pharmacological studies, NECA is employed to investigate the physiological roles of adenosine receptors in various systems, including the cardiovascular, nervous, and immune systems. It is also used to explore potential therapeutic applications, such as modulating heart rate, reducing inflammation, and managing pain. Additionally, NECA helps in understanding the mechanisms of adenosine receptor-mediated effects in conditions like ischemia, asthma, and neurodegenerative diseases. Its broad receptor activation profile makes it a key compound in drug discovery and development targeting adenosine receptors.