IRL-1620 is primarily used in research settings to study the endothelin system, particularly focusing on its role in cardiovascular and neurological functions. It acts as a selective agonist for the endothelin B (ETB) receptor, making it valuable for investigating vasodilation, blood flow regulation, and vascular remodeling. In neuroscience, it is employed to explore its potential neuroprotective effects and its role in modulating cerebral blood flow, which is relevant in conditions like stroke or neurodegenerative diseases. Additionally, IRL-1620 is utilized in studies related to cancer research, as the endothelin system is implicated in tumor angiogenesis and progression. Its application helps in understanding the mechanisms of endothelial cell signaling and its implications in various pathological conditions.