[(3aS,4R,6aR)-2,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(2-fluorophenyl)methylamino]carbamate

95%

Reagent Code: #54773
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CAS Number 1003870-29-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 296.29 g/mol
Formula C₁₄H₁₇FN₂O₄
inventory_2 Storage & Handling
Storage 2-8°C, dry, sealed

description Product Description

This compound serves as a crucial intermediate in medicinal chemistry, particularly in the synthesis of HIV protease inhibitors such as Darunavir. It is employed in the development of antiretroviral drugs for treating HIV/AIDS, where it enhances the binding affinity to the viral protease enzyme, improving efficacy against drug-resistant strains. The unique bis-tetrahydrofuran structure provides rigidity and optimal positioning for hydrogen bonding interactions within the enzyme's active site. Additionally, the (2-fluorophenyl)methylamino group contributes to lipophilicity, aiding in bioavailability and cellular uptake. Research also explores its potential in other protease-targeted therapies, though its primary application remains in antiviral pharmaceuticals.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿41,940.00

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