Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly those targeting tyrosine kinases involved in cancer cell proliferation. Shows promise in the development of anti-tumor agents due to its ability to cross cell membranes and bind selectively to ATP-binding sites in target enzymes. Also employed in the study of metabolic stability and bioavailability of spirocyclic compounds, aiding in the optimization of drug candidates for improved pharmacokinetic profiles.