1-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one
95%
Reagent
Code: #238171
CAS Number
1235141-24-8
blur_circular Chemical Specifications
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Molecular Information
Weight
303.16 g/mol
Formula
C₁₆H₂₂BNO₄
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Registry Numbers
MDL Number
MFCD18383577
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors. Its boronic ester group enables Suzuki-Miyaura cross-coupling reactions, allowing for the construction of complex aromatic and heteroaromatic systems found in bioactive molecules. The oxazine ring provides structural rigidity and can enhance metabolic stability in drug candidates. Commonly employed in medicinal chemistry for lead optimization in oncology and inflammatory disease targets.
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